: The play centers on the battle between a group of friends—including Jonathan Harker , Mina Murray , and Professor Van Helsing —against the "vampiric plague" Dracula brings to London.

The setting shifts to Whitby, England. A ghost ship runs aground, and a strange illness falls upon Lucy Westenra. Professor Van Helsing is summoned to diagnose her bizarre blood loss. Calcutt emphasizes the psychological toll on Mina Murray and Arthur Holmwood as they watch Lucy transform into an undead creature. Act III: The Hunt