No discussion of romance in TMKOC is complete without addressing the iconic and comedic "side-romance" that has defined the show: .
Krishnan Iyer and Babita Prasad represent a cross-cultural marriage between a South Indian scientist and a stylish Bengali woman.
The character of Anjali Taarak Mehta is integral to this universe. She is the educated, health-conscious, and loving wife of the show’s protagonist, Taarak Mehta. The role has been famously portrayed by two actresses: Neha Mehta, who played the character for eight years, and currently, Sunayana Fozdar, who took over the role and has been praised for bringing a fresh energy to the character. The show is a certified family entertainer, holding the top spot in TRP charts even after 17 years, beating popular dramas like Anupamaa with 2.2 million ratings. Audiences describe TMKOC as "a complete family entertainer and a show which can be watched with kids and persons of all age".
Taarak Mehta, the show's narrator and Jethalal's "Fire Brigade" (problem solver), shares a unique marital dynamic with his wife, Anjali.