No. You will need to download the newer version of the installer on an internet-connected device and copy it over to update the software. To help tailor this guide further, let me know:

The offline installer allows IT managers to push silent installations via Group Policy Objects (GPO), Microsoft Endpoint Configuration Manager (SCCM), or simple batch scripts.

To understand the "hot" demand for the offline variant, one must analyze the limitations of the standard web installer.

Yes. AnyDesk is fully optimized for both 32-bit and 64-bit versions of Windows 10. Can I update AnyDesk offline?

: Allows you to keep a specific "hot" version of the installer on a USB drive for consistent deployment across different hardware. How to Download and Install AnyDesk on Windows 10

Using the AnyDesk offline installer for Windows 10 solves this problem. It allows you to install the full software without an active internet connection. This guide covers everything you need to know about downloading and using the offline setup safely. Why Use the AnyDesk Offline Installer?

Install the software on completely isolated machines.

: Optimized for high frame rates and smooth control.