This is the most critical step. Windows 10 64-bit typically blocks the installation of the older virtual USB bus drivers required for the Wilcom dongle.
Temporarily disable your antivirus software during the installation process, as it may interfere with the installation. How To Install Wilcom E2 In Windows 10 64 Bit LINK
If a Windows Security message appears, click "Install this driver anyway". This is the most critical step
Disclaimer: This guide is for educational purposes. Always use licensed software. How To Install Wilcom E2 In Windows 10 64 Bit LINK
If the installer hangs during the CorelDraw portion, install CorelDraw X5 separately in compatibility mode.